A crystalline lens subluxation can be associated with multiple systemic factors and hence systemic evaluation is required fin addition to just eye examination. Some systemic factors that cause lens subluxation have been mentioned on another post of this website. So the systemic investigations will be the following.
CBC - due to increased incidence of thormboembolic events in general anesthesia.
Serum or urine homocystein levels - to rule out homocysteinurea.
VDRL - So lens subluxation caused by syphilis.
Echocardiography - The ejection fraction must be adequate for patient to be operated under general anesthesia.

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