How to differentiate an antigen from an epitope.

It is a commonly confused point while discussing uveitis in eye that either the immune cells in anterior chamber of the eye are stimulate by an antigen or an epitope. Lets make this confusion a piece of cake.

Antigen	Epitope
An anitgen is a substance that is capable of stimulating an immune response	Also known as antigen determinant. It is part of antigen that is recognised by immune system especially by anti-body B or T Cells
Two Main types: Foreign antigen Auto-antigen	Two Main types: Conformational Linear
The amount of immune response stimulated depends upon kind and amount of antigen, route of entry in the body and individual characteristic of the individual

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Flash cards of high yield points for FCPS II

Posterior capsular rupture

The Mittendorf dot

The Mittendorf dot, determined by William Frederick Mitttendorf, is a congenital vascular abnormality of eye which takes place because of an involutional fault of the anterior terminus of anterior hyaloid artery. It manifests as a focal opacity in the infero-nasal element of the posterior lens capsular surface. It is a scientific version of persistent fetal vasculature (PFV), a spectrum of situations that rise up whilst fetal hyaloid vasculature fails to involute. The Mittendorf dot is concept to be connected to the posterior lens capsular surface itself; current research suggests the opportunity of a retrolental presence of the dot inside the anterior vitreous. A lone Mittendorf dot is a exceptionally benign clinical finding and no inflicting any visual impairment

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